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Showing posts from February, 2015

PTEN in Low Grade Gliomas

I came by this study by mistake, i certainly haven't been looking for more evidence of a shorter survival for me. it just appears every now and then when i'm online. i was actually studying mTOR pathways at the time. i should be studying for my clinical assessment this month but i've been having really bad headaches so i got drawn back into the whole cancer world again unfortunately. i wanted to be a statistical outlier but my genetics suggest that if i'm going to be an outlier then it would be at the wrong end of the graph. ''Correlation between molecular markers was determined using the mann-whitney U and spearman rank correlation tests. eight of the 26 patients with methylated PTEN died during the study as compared to the 1 of 19 without methylation. There was a trend towards statistical significance with PTEN methylated patients have decreased survival (P=0.128)'' http://www.ncbi.nlm.nih.gov/pubmed/19705067 basically PTEN suppresses the mTOR pat